MD-MATRIX - Tropokolagen Guna 10x2ml

This is the clinic pack 10×2 ml (lower unit price, free delivery). Also available as a single-session ampoule: MD-MATRIX Tropocollagen Guna 1×2 ml.

What is MD-MATRIX and how does it work?

MD-MATRIX Tropocollagen is a preparation for needle mesotherapy by Italian company GUNA Medical Device (Milan), specialising in aesthetic preparations based on physiological active ingredients. Designed for intradermal and subcutaneous injections in cellulite areas — it acts at the extracellular matrix (ECM) level, rebuilding the connective tissue structure responsible for skin elasticity and firmness.

The 10×2 ml pack is the preferred choice for practices running regular anti-cellulite programmes — lower unit price and sufficient stock for a complete treatment cycle for one or more patients.

Tropocollagen – the foundation of the collagen matrix

Tropocollagen is the fundamental structural unit of collagen fibres — a collagen precursor in the form of a triple polypeptide helix. Its lower molecular weight enables deeper tissue penetration after injection and direct fibroblast activation via mechanotransduction, triggering a cascade of neocollagenogenesis (new collagen synthesis) and neo-elastinogenesis. The result is dermal matrix rebuilding, cellulite reduction and improved connective tissue elasticity.

Citric acid and nicotinamide – metabolic synergy

• Citric acid — key metabolite of the Krebs cycle: increases ATP production, accelerates fibroblast metabolism, improves microcirculation and normalises the tissue environment in the cellulite area.
• Nicotinamide (vitamin B3) — precursor of NAD⁺ and NADP⁺: potent antioxidant action, improved tissue oxygenation and lymphatic microcirculation, lipid metabolism normalisation — key processes in cellulite pathogenesis.

Why choose MD-MATRIX 10×2 ml?

• lower unit price — meaningful savings for regular anti-cellulite programmes,
• free delivery — no shipping cost on the clinic pack,
• stock for a full cycle — 10 ampoules cover a complete 6–10 session programme,
• reduction of cellulite and "orange peel" skin,
• firming and regeneration of connective tissue on thighs, buttocks and abdomen,
• cellular-level action: neocollagenogenesis + metabolism + antioxidation.

Indications and treatment areas

• Indications: grade I–III cellulite, "orange peel" skin, connective tissue laxity, subcutaneous microcirculation disorders.
• Treatment areas: thighs (inner and outer), buttocks, abdomen, knee area, upper arms, sub-breast area.

Treatment protocol

• Administration: needle mesotherapy — intradermal and subcutaneous injections in the cellulite area.
• Dosage: 1 ampoule (2 ml) per session. The 10×2 ml pack = complete cycle of 6–10 sessions.
• Cycle: 6–10 sessions at 7–14 day intervals, followed by maintenance sessions every 1–2 months.

Composition and package contents

• Tropocollagen — collagen fibre precursor, fibroblast stimulation, neocollagenogenesis
• Citric acid — Krebs cycle, cellular metabolism, microcirculation
• Nicotinamide (vitamin B3) — antioxidation, tissue oxygenation, lipid metabolism
• Contents: 10 × ampoule 2 ml (20 ml total)
• EAN: 8033875150442
• Manufacturer: GUNA Medical Device, Via Palmanova 71, 20132 Milan, Italy
• Leaflet: Download PDF leaflet ↓

Also available as a single-session ampoule: MD-MATRIX Tropocollagen Guna 1×2 ml.

Contraindications

• pregnancy and breastfeeding,
• active infections or skin inflammation at the injection site,
• hypersensitivity to any component,
• autoimmune diseases,
• blood coagulation disorders.

FAQ – questions and answers

How many sessions does the 10×2 ml pack cover?

The pack contains 10 ampoules of 2 ml each. At the standard protocol of 1 ampoule per session, it covers a complete cycle of 6–10 treatments for one patient, or individual sessions for several patients. Exact dosage is determined by the specialist based on the area and cellulite grade.

Why does MD-MATRIX work better than topical anti-cellulite products?

Cellulite is a structural disorder of subcutaneous tissue — topical preparations cannot penetrate the stratum corneum to reach the deeper layers where the key pathogenic processes occur. MD-MATRIX delivered directly into tissue by mesotherapy injection acts at ECM level: stimulates neocollagenogenesis (tropocollagen), activates cellular metabolism (citric acid) and improves lymphatic microcirculation (nicotinamide) — simultaneously.

When are results visible?

Initial skin smoothing and reduced cellulite visibility is typically visible after 3–4 sessions. The full connective tissue firming and regeneration effect builds over several weeks after completing the cycle. Maintenance sessions are recommended every 1–2 months.

How does MD-MATRIX differ from MD-TISSUE Tropocollagen?

Both are GUNA Medical Device preparations based on tropocollagen but differ in their indication profiles: MD-MATRIX is specifically formulated for cellulite and subcutaneous body tissue (thighs, buttocks, abdomen), while MD-TISSUE is primarily indicated for facial and neck skin regeneration (scars, ageing). They contain different co-formulants tailored to those indications.

This product may only be used by doctors and cosmetologists trained in aesthetic medicine and holding qualifications to perform injections or mesotherapy. By purchasing this product you confirm that you hold the required professional qualifications.

• What is MD-MATRIX and how does it work?
• Tropocollagen – the foundation of the collagen matrix
• Citric acid and nicotinamide – metabolic synergy
• Why choose MD-MATRIX 10×2 ml?
• Indications and treatment areas
• Treatment protocol
• Composition and package contents
• Contraindications
• FAQ – questions and answers