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  • Radiesse 1x1.5 ml with lidocaine

Radiesse with lidocaine is an advanced tissue stimulator from Merz Aesthetics based on microsphere calcium hydroxyapatite (CaHA) in a gel matrix.

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Radiesse 1×1.5 ml with lidocaine – CaHA tissue stimulator, dual-action, volumetry and collagenesis

Radiesse by Merz Aesthetics is one of the best-documented tissue stimulators in aesthetic medicine — based on calcium hydroxyapatite microspheres (CaHA) suspended in a carboxymethylcellulose gel matrix. Dual-action: immediate filling and long-term collagen stimulation. Lidocaine 0.3% for procedural comfort. Free delivery. For qualified professionals only.

Radiesse 1x1.5ml with lidocaine tissue stimulator CaHA calcium hydroxyapatite Merz Aesthetics volumetry collagen

ℹ️ Packaging update in progress: The external packaging of Radiesse+ Lidocaine is being updated. The outer box may differ from the product image — the formula, composition and mechanism of action remain unchanged. Also available without lidocaine.

What is Radiesse and how does it work?

Radiesse is a second-generation tissue stimulator and filler based on calcium hydroxyapatite (CaHA) — a compound naturally found in human bones and teeth. It acts in two stages:

  • Stage 1 — immediate filling effect: The carboxymethylcellulose (CMC) gel matrix acts as a conventional filler — shaping facial contours, restoring volume and correcting wrinkles and folds immediately after injection,
  • Stage 2 — long-term collagen stimulation: CaHA microspheres create a scaffold that stimulates fibroblasts to synthesise new collagen, gradually thickening the skin and restoring its elasticity — an effect that persists well beyond the gel itself.

Why calcium hydroxyapatite (CaHA)?

  • Natural body component — CaHA is biocompatible and well-tolerated,
  • No animal-derived ingredients — minimises allergy risk,
  • Biodegradable — gradually absorbed by the body,
  • Unique collagen-inducing capacity — beyond filling, actively improves skin quality,
  • Long-lasting effect — neocollagenesis extends results far beyond conventional HA fillers,
  • Established safety history — FDA cleared (2006) · CE marked (2004).

Lidocaine 0.3% – built-in procedural comfort

The lidocaine version contains 0.3% lidocaine hydrochloride — a local anaesthetic that acts immediately upon injection and significantly reduces pain. Allows comfortable application without additional topical anaesthetics or regional blocks.

Indications and treatment areas

  • Facial volumetry and contouring — cheeks, chin (projection and definition), jawline,
  • Lifting and skin density improvement — restoring firmness and elasticity,
  • Deep wrinkles and folds — nasolabial folds, deep mimic lines,
  • Marionette lines,
  • Brow lifting,
  • Non-surgical rhinoplasty — bridge and tip shaping,
  • Hand rejuvenation and regeneration,
  • Acne scars.

Composition and package contents

  • Active substance: calcium hydroxyapatite microspheres (CaHA) in carboxymethylcellulose (CMC) gel
  • Lidocaine: 0.3% (lidocaine hydrochloride)
  • Contents: 1 × sterile prefilled syringe 1.5 ml
  • EAN: 4046222337957
  • Approvals: FDA (2006) · CE (2004)
  • Manufacturer: Merz North America Inc., 4133 Courtney St., Suite 10, Franksville WI 53126, USA
  • Responsible person (EU): Merz Aesthetics GmbH, Eckenheimer Landstraße 100, 60318 Frankfurt am Main, Germany

FAQ – questions and answers

How does Radiesse differ from classic HA fillers?

Classic HA fillers provide volume correction and are gradually absorbed without further skin effect. Radiesse acts in two stages: beyond immediate filling, its CaHA microspheres actively stimulate new collagen production by fibroblasts — an effect that builds over months. The skin doesn't simply return to baseline; it develops its own strengthened collagen scaffold.

How long do Radiesse results last?

Results are exceptionally durable thanks to collagen stimulation — typically 12–18 months or longer, depending on treatment area, lifestyle and individual metabolism. Hand rejuvenation effects may persist up to 2 years.

Can Radiesse be diluted for skin biorevitalisation?

Yes — there are established protocols for diluting Radiesse (with saline or lidocaine) for CaHA skin biostimulation treatments that improve skin quality and texture. This is an advanced technique requiring appropriate specialist training.

Why choose the lidocaine version?

Lidocaine 0.3% in the preparation reduces pain during injection — especially valuable for deeper volumetric treatments in more sensitive areas (cheeks, chin, jawline). Built-in anaesthesia eliminates the need for additional topical creams and shortens preparation time.

Information for professionals

Radiesse with lidocaine is intended exclusively for use by doctors and cosmetologists trained in aesthetic medicine holding qualifications to perform deeper subcutaneous injections. Apply with a needle or cannula depending on the treatment area. Dosage is determined individually per patient. By purchasing you confirm required professional qualifications.

Manufacturer details

Merz North America Inc.
4133 Courtney St., Suite 10
WI 53126 Franksville
United States

contact.usa@merz.com

Responsible person

Merz Aesthetics GmbH
Eckenheimer Landstraße 100
60318 Frankfurt am Main
Germany

service-aesthetics@merz.de

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