Mastelli Plinest One 5x4ml

Plinest One 5×4 ml — clinic pack for full treatment series (5 sessions × 4 ml). Single-vial Plinest options: Plinest 1×2 ml (biorevitalisation) · Plinest Fast 1×2 ml (faster formula).

What is Mastelli Plinest One and what makes the 5×4 ml format special?

Mastelli Plinest One is an injectable biostimulating preparation based on the patented PN-HPT® (Polynucleotides Highly Purified Technology). The 5 × 4 ml clinic pack is designed for comprehensive treatments covering large areas (face, neck, décolletage and hands in a single session) or full treatment series without restocking.

PN-HPT® polynucleotides act at the cellular level:

• Intensive cellular regeneration — polynucleotides provide substrate for cell repair and renewal, accelerating natural biological skin processes,
• Collagen production stimulation — fibroblast activation for new collagen fibre synthesis, improving structure and elasticity,
• Deep hydration — improved skin moisture retention,
• Skin tone evening and radiance restoration — normalisation of processes responsible for complexion brightness,
• Repair mechanism reinforcement — supporting natural skin recovery after treatments and environmental exposure.

The Plinest range – which preparation to choose?

Indications and treatment areas

• Skin laxity and dehydration — restoring firmness and optimal hydration,
• Visible signs of ageing — slowing and correcting wrinkles and loss of elasticity,
• Uneven skin tone and loss of radiance — brightening, tone evening, complexion refresh,
• Post-aesthetic-treatment regeneration support — rebuilding the skin barrier and accelerating recovery,
• Tissue biostimulation — activating the skin's own repair processes.

Treatment areas: face · neck · décolletage · hands

Treatment protocol

• Series: 3–4 sessions every 2–3 weeks,
• Results: full effects visible after completing the therapy series,
• Volume per session: 4 ml — sufficient to cover face, neck, décolletage and hands in one visit,
• Route: intradermal injections.

Composition and package contents

• Active substance: Polynucleotides PN-HPT®
• Contents: 5 × prefilled syringe 4 ml
• EAN: 8053303261410
• Manufacturer: Mastelli S.r.l., Via Armea 90, 18038 Sanremo, Italy

FAQ – questions and answers

Why does Plinest One have 4 ml ampoules instead of 2 ml?

The 4 ml format is optimal for comprehensive multi-area sessions — face, neck, décolletage and hands. The larger volume allows the specialist to perform a full rejuvenating and biostimulating treatment in a single visit. The 5-unit pack covers a full 3–4 session series for one or several patients.

How does Plinest One differ from Plinest 1×2 ml?

Plinest One (5×4ml) is a clinic pack with large-volume ampoules for comprehensive biostimulating sessions targeting collagen, skin tone and lifting. Plinest 1×2 ml is the classic PN-HPT® 20 mg/ml biorevitalisation — a smaller, single-session vial ideal for precise biorevitalisation or series top-ups. Both are based on Mastelli's PN-HPT® technology and differ in ampoule volume and application profile.

Mastelli Plinest One is intended exclusively for use by doctors and cosmetologists trained in aesthetic medicine holding qualifications to perform intradermal injections. By purchasing this product you confirm that you hold the required professional qualifications.

• What is Mastelli Plinest One and what makes the 5×4 ml format special?
• The Plinest range – which preparation to choose?
• Indications and treatment areas
• Treatment protocol
• Composition and package contents
• FAQ