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Orthovisc is a sterile, non-pyrrogenic preparation for supply injection containing sodium hyaluronate (NaHA) 15 mg/ml (30 mg in 2 ml) produced by Anika Therapeutics (USA).

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Orthovisc 1×2 ml – sodium hyaluronate 15 mg/ml for intra-articular injections, synovial fluid substitute, osteoarthritis

Sterile, non-pyrogenic preparation by Anika Therapeutics (Bedford, MA, USA) for intra-articular injections containing sodium hyaluronate 15 mg/ml. Acts as a synovial fluid substitute — supports joint lubrication, reduces pain and improves mobility in osteoarthritis. Medical device. For professional use by a physician or qualified specialist only.

Orthovisc 1x2ml 30mg/2ml sodium hyaluronate 15mg/ml intra-articular injections synovial fluid substitute osteoarthritis knee joint

Need two packs? Buy the Orthovisc Twin Pack 2×2 ml (259 PLN) and save.

How does Orthovisc work? The viscosupplementation mechanism

In osteoarthritis, natural synovial fluid loses its rheological properties — it becomes thinner, less elastic and lubricates cartilage less effectively. Orthovisc contains sodium hyaluronate (NaHA) 15 mg/ml — a long-chain polymer that supplements and restores synovial fluid properties:

  • Viscosupplementation — replenishing volume and restoring viscoelastic properties of synovial fluid,
  • Friction reduction — better joint surface lubrication reduces cartilage wear and loading,
  • Mechanical cushioning — hyaluronate absorbs and distributes loads acting on the joint,
  • Pain reduction — decreasing pain stimuli from friction and overloading,
  • Biocompatibility — sodium hyaluronate is a natural component of synovial fluid; does not interfere with healing.

Composition and physicochemical parameters

Parameter Value
Active substance Sodium Hyaluronate (NaHA) 15 mg/ml
Per syringe 30 mg NaHA / 2 ml
Osmolarity 340 mOsm
Base Saline solution
Preparation Sterile, non-pyrogenic; needle not included

Indications and therapeutic effects

  • Osteoarthritis (osteoarthrosis, arthrosis),
  • Joint pain and restricted mobility,
  • Synovial joint dysfunction,
  • Reduced quantity or quality of synovial fluid,
  • Mechanical joint overloading,
  • Discomfort during movement.

Therapeutic effects: pain reduction · improved joint mobility and function · joint surface lubrication support · friction reduction · reduced mechanical loading · improved comfort of movement · long-lasting effects after a full treatment cycle.

Treatment protocol and contraindications

  • Route: intra-articular injection (by physician or qualified specialist only),
  • Treatment cycle: 3 injections — best results after completing the full cycle,
  • Note: needle not included in pack.

Main contraindications: hypersensitivity to ingredients · skin or joint infection at injection site · active inflammation · coagulation disorders / anticoagulants (without medical consultation) · pregnancy and breastfeeding (without physician decision) · fever or active systemic infection.

Package contents

  • Contents: 1 × prefilled syringe 2 ml (30 mg NaHA)
  • EAN: 817337000036
  • Manufacturer: Anika Therapeutics, Inc., 32 Wiggins Avenue, MA 01730 Bedford, USA
  • CE-marked medical device

Twin pack: Orthovisc Twin Pack 2×2 ml (259 PLN).

FAQ – questions and answers

What is viscosupplementation and how long do results last?

Viscosupplementation is the direct intra-articular injection of hyaluronate to supplement depleted synovial fluid. After Orthovisc administration, hyaluronate forms a protective layer on cartilage surfaces, reduces friction and absorbs mechanical loads. Results after a full 3-injection cycle may persist for several months — individually depending on disease severity and patient lifestyle.

How does Orthovisc compare to Durolane and Cingal?

All three are HA-based viscosupplementation preparations differing in concentration, molecular weight and protocol. Orthovisc (15 mg/ml, 3 injections) is the classic multi-injection approach. Durolane (20 mg/ml, cross-linked) is a single-injection extended-action product. Cingal (22 mg/ml HA + triamcinolone) combines viscosupplementation with a corticosteroid component for faster pain relief. Selection depends on clinical preference and specialist protocol.

Information for professionals

Orthovisc is a medical device intended exclusively for use by a physician or appropriately qualified specialist with authorisation to perform intra-articular injections. The preparation should be injected slowly into the target joint space using a sterile, single-use needle of appropriate size (not included). By purchasing, you confirm you hold the required professional qualifications.

Manufacturer details

Anika Therapeutics, Inc.
32 Wiggins Avenue
MA 01730 Bedford
United States

customerservice@anika.com

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